Translational genomics of neurodevelopmental disorders
Welcome to our lab site!
We are a highly motivated and interdisciplinary research team that focuses on dissecting molecular networks and mechanisms underlying human brain function and disease, using the fruitfly Drosophila melanogaster as a model. Here you can read more about what we do.
We are based in the Department of Human Genetics at Radboudumc in Nijmegen, The Netherlands. In addition, we are embedded in the multidisciplinary Donders institute of Brain, Cognition, and Behaviour, which allows us to operate across disciplines.
Recent highlights
2025
Feb - The February edition of the Radbode (the journal of the Radboudumc) featured an article on the GTF3C3 paper by Laura, Adela and Mireia, including interviews with Annette and a patient's parent.
Feb - We sadly said goodbye to our technician Franziska, but were happy to welcome previous intern Pleuni as our new technician! We wish Franziska a great time at her new position at the MPI in Münster.
Jan 24 - Part of the lab joined for the REPURPOLIS Drug Repurposing Game, organized by Eatris; a game about the path to successfully bring a repurposing drug candidate from academia to the patient. Very fun and insightful.
2024
Dec 17 - Christmas event by the Academic Alliance Genetics (Radboudumc and MUMC) in Limburg
Dec 10 - The lab celebrated Sinterklaas with poems, gifts, and traditional Dutch stamppot.
Dec 5 - Adela, Laura, Mireia, and Annette received a great gift from Sinterklaas: the GTF3C3 paper is out! Press release by the Radboudumc here.
More news here
Events we look forward to
March - Collective lab cleaning and pizza!
March-June - Nicholas will be visiting the Préat & Plaçais group in Paris to learn live imaging and to identify metabolic dysregulation associated with several neurodevelopmental genes.
April 3-5 - Marina will (digitally) join the Genetics of Neurodevelopmental Disorders conference
June 5-6 - Annette will present at the Kleefstra Syndrome Confererence 2025 in Spain.
June 19 - Annette will give a presentation at the FOXP1 conference in Ijmuiden.
Sept 25-28 - The European Drosophila Research Conference in Alicante! Nicholas will participate, and Annette will co-chair the session on disease models.
2026
Sept - Neurofly '26 in Cologne! Annette is involved in the organization.
